索引：内皮细胞特异性分子1抗体用途

中文名称    内皮细胞特异性分子1抗体    

英文名称    ESM1    

别    名    Endocan; Endothelial cell specific molecule 1; ESM 1; ESM-1; ESM 1 secretory protein; ESM1 secretory protein; ESM1_HUMAN; Endothelial cell-specific molecule 1.    

供 应 商    远慕生物

研究领域    心血管  免疫学  细胞粘附分子  内皮细胞      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Horse,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 内皮细胞特异性分子1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    20kDa    

细胞定位    分泌型蛋白     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human ESM1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

内皮细胞特异性分子1抗体产品介绍    background:

ESM1 is a secreted dermatan sulfate proteoglycan which is predominantly expressed in the endothelial cells in human lung and kidney tissues. Expression of ESM1 is regulated by cytokines. ESM1 may have a role in lung endothelial cell-leukocyte interactions. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.

Function:
May have potent implications in lung endothelial cell-leukocyte interactions.

Subunit:
Monomer.

Subcellular Location:
Secreted. Peroxisome.

Tissue Specificity:
Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney.

Post-translational modifications:
May contain intrachain disulfide bonds.

Similarity:
Contains 1 IGFBP N-terminal domain.

Database links:
UniProtKB/Swiss-Prot: Q9NQ30.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.