远慕推荐：嗜酸性粒细胞阳离子蛋白抗体

中文名称    嗜酸性粒细胞阳离子蛋白抗体    

英文名称    EAR1    

别    名    ECP1_MOUSE; Cytotoxic ribonuclease; Eosinophil cationic protein 1; Eosinophil secondary granule ribonuclease 1; EAR-1; Ribonuclease 3-1; RNase 3-1; eosinophil cationic protein 1 precursor; Ear1; ECP 1.    

供 应 商    远慕生物

研究领域    细胞生物  免疫学  通道蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Mouse, Rat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 嗜酸性粒细胞阳离子蛋白抗体（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    14kDa    

细胞定位    分泌型蛋白     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from mouse Eosinophil cationic protein 1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

嗜酸性粒细胞阳离子蛋白抗体产品介绍    background:

Eosinophil derived neurotoxin (EDN) is a protein belonging to the ribonuclease (RNase) A superfamily. It has recently been found to have antiviral activity against respiratory syncytial virus and human immunodeficiency virus in vitro.

Function:
Cytotoxin and helminthotoxin with ribonuclease activity. Possesses a wide variety of biological activities.

Subunit:
Interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). In vitro interacts with and insert into lipid bilayers composed of dioleoyl phosphatidylcholine and dioleoyl phosphatidylglycerol. In vitro, tends to form amyloid-like aggregates at pH 3, but not at pH 5, nor 7.

Subcellular Location:
Secreted. Note=Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus.

Similarity:
Belongs to the pancreatic ribonuclease family.

Gene ID:
13586

Database links:
Entrez Gene: 13586 Mouse