抑癌蛋白DKK3抗体应用方法

中文名称    抑癌蛋白DKK3抗体   
 
英文名称    DKK3   

别    名    Dickkopf 3; Dickkopf homolog 3; Dickkopf related protein 3; Dickkopf related protein 3 Precursor; Dickkopf3; DKK 3; DKK3; hDkk 3; hDkk3; REIC; RIG-like 5-6; RIG-like 7-1; DKK3_HUMAN; Dickkopf 3 homolog (Xenopus laevis); Dickkopf homolog 3; Dickkopf-3; Dickkopf-related protein 3; Dkk-3; hDkk-3; Regulated in glioma; RIG.    

供应商     远慕生物      

研究领域    肿瘤  细胞生物  免疫学  信号转导  转录调节因子      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 抑癌蛋白DKK3抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    36kDa    

细胞定位    分泌型蛋白     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human DKK3    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

抑癌蛋白DKK3抗体产品介绍    background:

Dickkopf 3, like DKK1, DKK2, and DKK4, possesses an N terminal signal peptide and 2 conserved cysteine rich domains, which are separated by a linker region and contain 10 cysteine residues each. The second cysteine region has a putative lipid binding function that may facilitate WNT/DKK interactions at the plasma membrane. The linker region contains 50 to 55 amino acids in DKK1, DKK2, and DKK4, whereas in DKK3 it contains only 12 amino acids. All DKKs have several potential sites for cleavage by furin type proteases.

Subunit:
Interacts with LRP5 and LRP6.