7脱氢胆固醇还原酶抗体说明书

【中文名称】7脱氢胆固醇还原酶抗体
【英文名称】Anti-DHCR7
【研究领域】肿瘤免疫学细胞凋亡
【抗体来源】Rabbit
【克隆类型】Polyclonal
【交叉反应】Human,Mouse,Rat,Dog,Pig,Cow,Horse,GuineaPig,
【产品应用】WB=1:100-500ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（石蜡切片需做抗原修复）
notyettestedinotherapplications.
optimaldilutions/concentrationsshouldbedeterminedbytheenduser.
【分子量】57kDa
【细胞定位】细胞核细胞浆
【性状】LyophilizedorLiquid111
【浓度】1mg/1ml
【免疫原】KLHconjugatedsyntheticpeptidederivedfromhumanAPI5
【亚型】IgG
【纯化方法】affinitypurifiedbyProteinA
【储存液】0.01MTBS(pH7.4)with1%BSA,0.03%Proclin300ａnd50%Glycerol.

保存条件Storeat-20°Cforoneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthａndforgreaterthanayearwhenkeptat-20°C.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibodytheantibodyisstableforatleasttwoweeksat2-4°C.

【产品介绍】7脱氢胆固醇还原酶抗体Apoptosisinhibitor5(API5)isanantiapoptoticfactorwhichmayhavearoleinproteinassembly.7脱氢胆固醇还原酶抗体API5expressionisoftenupregulatedintumorcells,particularlyinmetastaticcells.ItisacriticaldeterminantofE2F1-inducedapoptosis,actingdownstreamofE2FtosuppressE2F-dependentapoptosiswithoutgenerallyblockingE2F-dependenttranscription.AlternateNames:AAC11;AAC11;Antiapoptosisclone11protein;API5;API5;API5like1;API5L1;Cellmigrationinducinggene8protein;Fibroblastgrowthfactor2interactingfactor2;FIF;MIG8;MIG8;MigrationinducingproteinMIG8;ProteinXAGL.