组织蛋白酶E抗体说明书

英文名称：Anti-CathepsinE
中文名：组织蛋白酶E抗体
别名：CathepsinE;CATE;CTSE;EC3.4.23.34;Erythrocytemembraneasparticproteinase.
规格：0.1ml/100μg,0.2ml/200μg
交叉反应：hu,rat,mo
产品类型：一抗
应用领域:/合成与降解
蛋白分子：predictedmolecularweight:42kDa
浓度值：1mg/1ml
物理性状：LyophilizedorLiquid
免疫原：KLHconjugatedsyntheticpeptidederivedfromhumanCathepsinEC-terminus
亚型：polyclonal
纯化方法：affinitypurifiedbyProteinA
保存液：0.01MPBS,pH7.4with10mg/mlBSAａnd0.1%Sodiumazide
应用技术：//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/notyettestedinotherapplications./optimaldilutions/concentrationsshouldbedeterminedbytheenduser.
保存环境：Storeat-20°Cforoneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthａndforgreaterthanayearwhenkeptat-20°C.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibodytheantibodyisstableforatleasttwoweeksat2-4°C.

产品介绍：CathepsinEisanintracellularasparticproteaseofthepepsinfamily,whichisstructurallyhighlyhomologoustothelysosomalasparticproteasecathepsinD.CathepsinEislessabundantthanCathepsinDａndhasamorelimiteddistribution,whichincludeslymphoidtissues,gastrointestinaltracttissue,bloodcells,microgliaａndactivatedBlymphocytes.ItisnotexpressedinrestingBlymphocytes.CathepsinEmayhavearoleinimmunefunction.ItismostlikelyinvolvedintheprocessingofantigenicpeptidesduringMHCclassII-mediatedantigenpresentation.Itmayalsoplayaroleinactivation-inducedlymphocytedepletioninthethymus,ａndinneuronaldegenerationａndglialcellactivationinthebrain.